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The rifampin in the semen will not cause any problems, but their semen may not be safe to ingest. Rifampin is an antibiotic given for many reasons, including STD's. If the rifampin is being given for an STD then it would not be safe to ingest the semen, not because it has the rifampin in it, but because it may still have infectious particles in it.

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Q: Is it safe to swallow someone's semen if they are taking Rifampin due to the fact it can change the color of semen to an orange-red?
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