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It depends. Fresh air is always a good idea. However, if the window is open, without a screen, insects can enter the home and infect the sleeper. One example is mosquitoes which can transmit a number of infections, some of which are deadly (Eastern equine encephalitis, Japanese encephalitis, La Crosse encephalitis, St. Louis encephalitis, West Nile virus, Western equine encephalitis, Dengue Fever, malaria, etc.)
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