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Helium isn't toxic to the body but does deprive it of needed oxygen. By inhaling Helium you are actually pulling oxygen out of the body and can be potentially dangerous if oxygen isn't reintroduced. As the related link states, sucking it in from a Helium balloon won't kill you. You might just get light-headed or pass out (don't hit your head). Inhaling it from a tank or climbing into a giant Helium balloon is extremely dangerous and there are fatal cases.

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Q: Is helium bad for your body?
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