Is glutathione sublingual spray more effective and safe?

Answer 1

"The short answer is no. Not if you are trying to get it into your cells where is can do the most good.

Glutathione does not pass through the cell walls so what we can do is take the pre cursors to create glutathione in our cells. The latest product can release glutathione "on demand", as your body requires."

This is not necessarily true. Sure, oral Glutathione is broken down is the gut, mostly. However by giving a high enough dose, some will be absorbed.

The sublingual route has real possibilities for delivering higher amounts - i.e. absorption through sublingual route is far more efficient.

IV injection is the most effective route still

This idea that glutathione cannot cross the cell "wall" is not relevant as animal cells do not have cell walls, but have membranes.

Whether exogenous glutathione can effect cells is highly debatable, however clinical studies seem to show a skin lightening effect even with oral doses. This implies that glutathione is doing something and must be effecting the cells.

It is definitely possible that glutathione receptors or carriers exist on the cell membrane. This has not really been studied.

In short the answer is YES it should be more effective, and it is most likely safe (as IV admin doesn't seem to give major problems)