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Dobutamine is a potent beta-agonist with major activity on the beta-1 (heart) and weaker activity on beta-2 (blood vessels and lungs) receptors. It also has weak alpha-1 activity (blood vessels).

The beta actions would cause an increase in heart rate and vasodilation. The alpha action could cause vasoconstriction but it would only be seen if the beta effects were over-ridden or opposed (for instance if the person was also on a beta blocking drug).

So, technically yes dobutamine could cause vasconstriction, but clinically it is unlikely.

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Q: Is dobutamine a vasoconstrictor
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