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If your question had to be read in this way, then the answer is:

Is germ a matter?

Answer: Yes, all cells are comprised of matters (particles)

And if your question is:

Does germ matter?

see answer!

Germs matter a lot.

What are 'germs' ?

Microorganism, especially a pathogen; see Germ theory of disease

Germ cell, an ovum or sperm, or one of its progenitors

The Germ (periodical), a periodical established by the Pre-Raphaelite Brotherhood to disseminate their ideas

Germ (mathematics), an object in a topological space that captures local properties

Cereal germ, the reproductive part of a cereal grain

Germ, Hautes-Pyrénées, a commune of the Hautes-Pyrénées département in southwestern France.

When it is PATHOGEN, and its function is pathogenic, it is harmful and dangerous for human and animals.

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