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No. They are two completely different drugs. GHB is one of the most commonly used date-rape drugs. It is a strong depressant that makes you black out for hours, and when you wake up you have no idea what you've been doing (or what has been done to you). Some people do take tiny amounts of GHB recreationally, though.
Ecstasy (MDMA) is a stimulant. You can't fall asleep on Ecstasy, nor will you black out on Ecstasy. It is also a mild hallucinogen, which GHB is not.
Basically, Ecstasy is for dancing at clubs and having fun, and GHB is for incapacitating people so you can rape them.
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