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We can't tell you which is "better" without a lot more detail.

For example, it doesn't matter how much more effective a 3 day treatment is than a 1 day treatment if you can only get 1 day off. And you haven't even told us what this "treatment" is or what it's for, so whether or not it's more effective or just spread out longer is an open question.

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Q: Is 3 day treatment better than 1 day?
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