Yes. Frequent use of laxatives will prevent the body from absorbing the nutrients it needs, and can lead to long-term gastrointestinal problems. Use of laxatives for other than short-term needs can be indicative of emotional issues that need attention from a mental health professional.
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Occasional use of a laxative whether needed or not is not dangerous, Regular use of bulk forming laxatives (metamucil, citrucel, etc) is OK. Regular use of stimulant laxatives (dulcolax tabs, citrate of mag, others) is not good- will cause premature aging and other intestinal problems.