Yes. I know this guy that started losing his hearing in his right ear from drinking too much of it from the bottle.
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By taking the normal recommended dosage of peptone bishop, the product should work within 20 minutes or up to an hour after consuming it.
Pepto-Bismol can be taken after meals, on either an empty or full stomach. There is no data to suggest Pepto-Bismol would interfere with the absorption of nutrients.