It varies, if you are playing tackle football it is more likelier than if you are playing tennis... Although, you never know when it is going to happen, it could happen without you even knowing!
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One can break their leg repeatedly. As it's an injury based on physics, there is no developed immunity.
If you're breaking your leg often, however, you might want to discuss this with your doctor and see if the problem is behavioral, physiological, or just bad luck.
Your arm can break a lot of times because it will always heal back into its regular condition.