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it depends on the strength of medicine Tylenol comes in 160 mg per 1 teaspoon so to equal 1000 mg it would take 6.25 teaspoon Benadryl comes in 12.5 mg per 1 tsp so it would take 80 tsp to equal 1000 mg each medicine has different strength mg is a dosage unit and tsp is a dosage measurement two different things
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