Best Answer

The halflife is between 0.7 and 1.2 hours. However, perfusion into various tissues allows for a peak plasma distribution if given IV every 6-8 hours. I'm guessing you're clear after 48 hours. Additional information:

As a general rule, steady-state plasma (or tissue) levels are reached after 5 half-lives and, conversely, non-pharmacologic concentrations are reached in the same amount of time.

IV medications complicate things somewhat, since peak and steady-state levels are reached immediately as the medication is delivered directly to the blood stream. Given the half life of Zosyn is 0.7-1.2 hours, and peak plasma concentration is reached immediately after the infusion, it should take 3.5-6 hours for the drug to be completely (or at least to the point of almost not being able to detect it) out of your system. If you look at the tables on the link below, this appears to bear out.

Tissue concentrations may vary, however - tissue concentrations are roughly 50-100 percent of plasma concentration and I cannot find any data to suggest it is more apt to stay in the tissues vs re-distributing to the bloodstream as plasma levels fall, so I have to assume that tissue concentrations follow plasma concentration, which gives us the same time-table. For completely being out of your system (not just pharmacologically out of your system), it probably is completely cleared by 24 hours after a single dose. Multiple doses may complicate the picture, however, and require more time for clearance. Renal function will also play a factor, as this drug is cleared by the kidney.

User Avatar

Wiki User

15y ago
This answer is:
User Avatar

Add your answer:

Earn +20 pts
Q: How long does iv zosyn take to get out of your system after stopping?
Write your answer...
Still have questions?
magnify glass
Related questions

If a patient is allergic to augmentin is it ok to take zosyn?


How long does it take for your adrenal glands to work after stopping prednisone?

how long does it take for your adrenal glands to start working after stopping predisone

How long does it take to get sex back after stopping codeine?

9 days

How long does it take to get pregnant after quieting birth control?

how long does it take to get back on your normal cycle after stopping birth control

How long does it take to drive from Washington DC to Pennsylvania?

It takes about 5 to 6 hours without stopping, of course if your interested in sightseeing and stopping it will take you about 8 to 10 hours.

Do you spot after stoping the pill?

Hi, Your question is: Do you spot after stopping the pill? Yes, you do spot after stopping the pill. The "spotting" usually occurs within 7 days of stopping the pill but sometimes it can take as long as 14 days to occur. This spotting is known as a withdrawal bleed and is perfectly normal. It simply means birth control is withdrawing from your system.

How long does it take pep spice to get out of your system?

How long does it take pep spice to get out of your system?

How long would it take from Montana to Pennsylvania driving?

Roughly a day or two. Depending on how long you can drive without stopping.

How long does it take to get a normal cycce after stopping contraceptives?

It usually takes 1-3 months.

How long does it take to get from the united kingdom to denmarK?

it depends on the speed your going and if you keep stopping on the road

How long does it take to get to somerset from sunderland?

Depending on traffic and stopping at services, allow 6 hours.

How long would it take to drive 263 miles at 65 mph?

4.05 hours with out stopping.