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Glyburide, a medication used to treat type 2 Diabetes, typically starts working within 30 minutes to 1 hour after ingestion. Its peak effect is usually reached within 2-4 hours after taking the medication. The duration of action of glyburide is approximately 24 hours, so it is usually taken once daily. It is important to follow your healthcare provider's instructions regarding the timing and dosing of glyburide for optimal effectiveness.
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