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How rare is myelofibrosis?

Myelofibrosis is rare, affecting fewer than 2 of 100,000 people in the United States. http://msd-bahamas.com/mmhe/sec14/ch178/ch178c.html


Can Myelofibrosis get worse?

Myelofibrosis can progress to acute lymphocytic leukemia or lymphoma


What are other names for Myelofibrosis?

Myelofibrosis goes by many names including idiopathic myelofibrosis, agnogenic myeloid metaplasia, chronic myelosclerosis, aleukemic megakaryocytic myelosis, and leukoerythroblastosis


What does Myelofibrosis stem from?

Myelofibrosis is caused by an abnormality in a single stem cell, which causes it to grow out of control


Is idiopathic myelofibrosis fatal?

Idiopathic myelofibrosis typically becomes progressively worse and can cause death


Does myelofibrosis always produce symptoms?

About one quarter of all patients with myelofibrosis have no symptoms (asymptomatic)


Is myelofibrosis easy to diagnose?

Because symptoms are similar to other diseases (mostly leukemias), myelofibrosis is not easy to diagnose


Does Bone marrow transplantation treat myelofibrosis?

Although historically there has not been much improvement in the treatment of myelofibrosis, that has changed recently. The main treatment now consists of taking a medication known as "Jakafi" which targets the gene thought to cause myelofibrosis.


What age does myelofibrosis set in?

Most patients with myelofibrosis are over 50 years old; the average age at diagnosis is 65 years


Is fatigue a symptom of myelofibrosis?

Yes


Is fever a symptom of myelofibrosis?

Yes


Is itchiness a symptom of myelofibrosis?

Yes