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Effects of Nicotine When a person inhales cigarette smoke, the nicotine in the smoke is rapidly absorbed into the blood and starts affecting the brain within 7 seconds. In the brain, nicotine activates the same reward system as do other drugs of abuse such as cocaine or amphetamine, although to a lesser degree. Nicotine's action on this reward system is believed to be responsible for drug-induced feelings of pleasure and, over time, addiction. Nicotine also has the effect of increasing alertness and enhancing mental performance. In the cardiovascular system, nicotine increases heart rate and blood pressure and restricts blood flow to the heart muscle. The drug stimulates the release of the hormone epinephrine, which further stimulates the nervous system and is responsible for part of the "kick" from nicotine. It also promotes the release of the hormone beta-endorphin, which inhibits pain. People addicted to nicotine experience withdrawal when they stop smoking. This withdrawal involves symptoms such as anger, anxiety, depressed mood, difficulty concentrating, increased appetite, and craving for nicotine. Most of these symptoms subside within 3 to 4 weeks, except for the craving and hunger, which may persist for months.

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15y ago
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12y ago

Nicotine changes how your brain and your body function. The net results are somewhat of a paradox: Nicotine can both invigorate and relax a smoker, depending on how much and how often they smoke.

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14y ago

It can addict you to what ever it is that has the nicotine in it.

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14y ago

makes your fingers yellow, gives you cancer if you smoke long enough, makes your hands shake

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14y ago

icarly.com will answer this question

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12y ago

Cancer which can lead to death.

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Q: How is nicotine harmful?
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