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There is a part of the brain called the hypothalamus which is next to the pituitary. When you have not enough Thyroxine (T4) your hypothalamus makes TRH which tells the pituitary to make Thyroid stimulating hormone (TSH).
TSH as in the name stimulates the thyroid gland in the neck to make more Thyroxine.
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What are thyroxine and triiodothyronine?
Thyroxine (T4) and triiodothyronine (T3) are hormones produced by the thyroid gland that regulate metabolism in the body. T4 is converted to the more active T3 in tissues, and both hormones play essential roles in controlling functions such as heart rate, body temperature, and energy levels. Imbalances in thyroxine and triiodothyronine levels can lead to various health issues, such as hypothyroidism or hyperthyroidism.
How the level of thyroxine in the blood affects the secretion of hormone TSH?
High levels of thyroxine in the blood negatively feedback to the pituitary gland, reducing the secretion of thyroid-stimulating hormone (TSH). Conversely, low levels of thyroxine signal the pituitary gland to increase TSH secretion to stimulate the thyroid gland to produce more thyroxine.
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