That depends on who you are writing it to. Is it a boss? An old friend? A family member? Depending on who it is addressed to is how formal or informal it should be.
Write it like you do like them!
you are awesome!
To write a goodbye letter you should include why you are leaving, how long you will be, and if possible, where you are going. You can also include a little history about something that was shared in the past.
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a good friend
The way you write goodbye in Greek is αντίο. You can also write goodbye in Spanish, which is adios or despedida.
Best wishes? Kind regards? Warm regards? They're endings I would use. To say "goodbye", I would just write "goodbye" and wish them well in everything they do.
Honestly and from the heart. If you do that, your next letter will be welcomed with open arms.
Grandma
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"Hola" is for hello "Adios" is for goodbye~