A blister hurts the worst when the raw skin contacts air. If the blister has popped, try to remove the loose skin and then put some cream or antibacterial ointment on it and cover it with a bandage (band aid). Keep covered for a few days, replacing bandage when needed. If the blister has not popped, you need to pop it but in a way you may find difficult. Take a sterilized needle and insert it in healthy skin (not affected by the blister) just outside the blister going under the blister to make a hole. After the hole is made via under the blister, squeeze all the fluid out through the hole. This will prevent the raw skin from contact with the air preventing added pain. You may need to do this a few times a day if the blister refills with fluid, but there should be no reason to cover with a bandage unless to prevent wearing against something.
This should heal in a few days and the top skin of the bubble can dry and come off.
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