If you are a layperson and see a "bubble" in IV tubing, you should report it to the nurse. Sometimes a bubble can be easily corrected; but other times, it can create additional problems. NOTE: if a "bubble" of air is large, or if there are many bubbles, it can push an air embolis into the bloodstream which can create a life-threatening condition!
A small bubble can be easily corrected, usually. Sometimes, the smallest bubble presents no risk unless there are many.
If you are a professional, or have been trained to do IVs for a family member, you can place your fingers (index and middle finger) above the bubble, and thumb and pinkie below the bubble -- lightly, don't squeeze the tube -- and tap the bubble with your index finger and thumb of your other hand. Be careful that you don't jar the needle / insertion site. After 1 or 2 taps, the bubble should rise and break up, with the air traveling upward, back toward the IV bag.
Again, if you are not trained, you should seek the advice of a trained medical person so that they can evaluate the tubing, IV flow, and the presence of the air "bubbles".
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