Typically just by eating them. Some people like to mix them with some other kind of food to cover up the bitter flavor, but a lot of people like to fast before they take them to avoid the stomach pains usually associated. Other people will boil the mushrooms and make a tea which is said to carry the same psychoactive effects but has less likelihood of causing severe stomach pains.
Some people also argue that you can smoke them, but no one has really proven that an effective method of imbibing them.
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DO NOT try to smoke or snort shrooms! especially snort. this may lead to mold growing in your lungs! highly avoided in the shroom culture!
They are just eaten straight, no preparation is required. You can mix them with food to make them more palpable (such as in a peanut-butter sandwich).