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Carrier-linked drugs are often activated through hydrolysis.

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7y ago

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What functional groups are the most common in prodrugs?

They are alcohols and carboxylic acids. They are usually activated by hydrolysis.


How can the hydrolysis rate of prodrugs be slowed down?

The hydrolysis rate of prodrugs can be slowed down with the usage of sterically hindered esters and the use of long-chain fatty acid esters.


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List of prodrugs user in cancer treatment?

Some cancer therapy prodrugs include: cyclophosphamide capecitabine dacarbazine - is ONLY converted to active form by the liver 5-Fluorouracil etoposide phosphate gemcitabine irinotecan - therapy relies on strongly active metabolites in addition to an active parent compound. These must be metabolized into an active metabolite in order to kill a cancer cell. Sometimes this occurs in the liver, but most of the above medications can be activated inside any cancer or normal cell also, so the expose their full anti-cancer effect locally, and hopefully avoid as many body-wide side effects. No drug is 100% safe.


Can activated abilities of artifacts be activated in this game?

Yes, activated abilities of artifacts can be activated in this game.


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Prodrugs are big reversible derivatives of drug molecules that undergo an enzymatic and/or chemical transformation in vivo to release the active parent drug, which can then exert the desired pharmacological effect. In both drug discovery and development, prodrugs have become an established tool for improving physicochemical, biopharmaceutical or pharmacokinetic properties of pharmacologically active agents. About 5-7% of drugs approved worldwide can be classified as prodrugs, and the implementation of a prodrug approach in the early stages of drug discovery is a growing trend. Thanks to some Pharmaceutical company's, they gave their ability to rapidly create proprietary prodrug versions of each these cannabinoids, they stand to benefit from emerging data and increasing recognition from the medical community of the potent pain relief and anti-inflammatory effects of cannabinoids.


Is you card activated?

yes you card is activated


What does uv activated mean?

activated by ultraviolet light


Why activated carbon is called activated?

Activated carbon has high surface area; this characteristic improve the reactivity of the material.


Do you have to activated and how it you can?

When one really has activated, and even as decided once to use even go, it is then that he really has been can activated.


Are there voice activated TVs?

yes there is a voice activated tv's


What is the pH for activated carbon?

Activated carbon hasn't a pH.