The evidence for it actually having a harmful effect is not what one might consider overwhelming, though a small percentage of people do have negative reactions (similar to, but not precisely like, an allergy) to it and some recent studies have suggested that it might be linked to hyperactivity in children (the evidence that it causes hyperactivity is weak to nonexistent; the evidence that it has an adverse impact on behavior of those who are already hyperactive is somewhat more substantial).
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