The strongest substance in the human body is DENTINE,a very hard material which resembles bone in composition but contain no haversian canals.The exposed portion of the tooth is covered with a thin layer of ENAMEL, which is even stronger than dentine. This hard part starts developing by forming a cap of predentine secreted by odonoblasts and enamel matrix formed on this predentine layer from ameoblsats.
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Enamel, the outer layer covering/protecting the crown of the teeth, is the hardest substance in the human body.