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The thyroid gland secretes both of these. Thyroxine or T4 is the most prevalent secretion of the thyroid - it is the inactive form of tri-iodothyronine (T3) which is important for regulation of metabolism. T3 and T4 are secreted by the follicular cells. Calcitonin is secreted by the parafollicular cells of the thyroid gland and acts to decrease blood calcium levels.
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