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Prolonged amphetamine abuse or abuse in high doses can cause problems including: * Toxic psychosis * Physiological and behavioral disorders * Dizziness * Pounding heartbeat * Difficulty breathing * Mood or mental changes * Unusual tiredness or weakness * Cardiac arrhythmias * Repetitive motor activity * Convulsions, coma, and death * Ulcers * Malnutrition * Mental illness * Skin disorders * Vitamin deficiency * Flush or pale skin * Loss of coordination and physical collapse

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