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Methylprednisolone helps reduce inflammation/swelling. Sciatica or Sciatic Neuritis is caused by general compression/irritation of sciatic nerve and most of the cases there are inflammation involve. Therefore oral steroid or methylprednisolone is very helpful for sciatica, however you cannot take methylprednisolone for long period of time, dose is usually tapered down after several days of using it, because steroid has many side effects that can be fatal. So you need to consult your doctor before taking methylprednisolone.
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