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If you take naproxen sodium more than once a week, you must immediately have your doctor or a hospital lab check your INR (prothrombin time) to know if your blood thinning is excessive. Normal is around 10 but if you have been prescribed Warfarin (Coumadin) for your heart condition, your level should probably be between 20 and 30. Higher levels can result in an internal hemorrhage.

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13y ago
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12y ago

The qualified answer is "yes"; no all interactions are fully understood but no interactions between warfarin and sleeping pills appear evident based on a cursory internet search.


Warfarin can interact with the following:

azole antibiotics, macrolides, quinolones, nonsteroidal anti-inflammatory drugs, including selective cyclooxygenase-2 inhibitors, selective serotonin reuptake inhibitors, omeprazole, lipid-lowering agents, amiodarone, and fluorouracil

There might also be an adverse interaction with cranberry juice, alcohol, borage and fish oil, and herbs such as, by example and without limitation, ginger, garlic, St. John's Wort, ginseng, and Ginko Biloba.

As long as warfarin has a LOT of interactions, it depens on which sleeping pill you want to take.

Although I would say any answer "based on a cursory internet search" shouldn't qualify as a "qualified answer" to any question, talking to your doctor definitely qualifies as a good course of action in getting an answer to your question.

Warfarin/Coumadin is a serious medication and your doctor no doubtedly stressed this when prescribing it. Like all medication, it interacts with everone differently, but it is more important to understand this with this drug because the dr. must get your blood to a certain consistency. Counteracting this drug or taking anything else to that thins the blood can cause your INR levels to be off. This can lead to two places, one; cause you to either bleed out (whether you know it or not) or clot unnecessarily (which can lead to a stroke or heart attack), or two; make it more difficult for the dr. to get your dosage right which can cause the same outcome.

You really should ask your doctor this question, and be specific in which sleep aid you are asking about. Even if you can't sleep and must stay awake until the doc decides it is time to go to work and answer phone calls, it's better to wait and get a correct answer than to quickly accept one based on internet searches.

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8y ago

Ask your doctor or a pharmacist before taking naproxen with warfarin.

Naproxen is used to treat pain or inflammation.

Warfarin is an anticoagulant used to stop blood from clotting.

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11y ago

Yes. I was prescribed Ambient CR while my doctor knew I was on Lovenox blood thinners.

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Q: Can you take sleeping pills with blood thinners?
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