Short answer: General rule of thumb with most medications is to give a 2-3 hour wait before taking anything else. This does seem to work for these 3 medications. However, be aware that doxycycline is very strong and stays in your system much longer than metronidazole. So you might want to give it more room to breath. If at all possible, I suggest waiting 4 hours after taking doxy before taking anything else, especially if you intend on taking probiotics or another supplement to replenish your immune system(which i highly suggest).
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