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Yes, but it would have no psychedelic effect, as the spores do not contain any hallucinogenic substances. Doing so would only put one at risk for getting sick (though its likely that nothing would happen).

Almost all spore syringes are suspended in distilled water, and believe it or not you already drink mushroom spores every day, and breathe them in as well. They are microscopic and as prevelant as pollen on the wind, so they tend to be on clothes, in your lungs, and even in your water. Of course the concentration of spores in a spore syringe is 1,000+ x higher, but it will have absolutely no effect since there is no psychoactive drug present.

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Q: Can you drink a syringe of mushroom spores?
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