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LSD acts on serotonin, a neurotransmitter. Exactly how it works is unknown. I am not aware of a case of induced "crazyness", but it can make some existing psychological conditions worse, if not permanently, at least temporarily. And as it acts at a very fundamental level within the brain, it's not likely we'll know what damage it does or does not do. At this time, we assume that LSD does not leave lasting physiological damage, but that's today's opinion -- in the 1960's it was thought LSD did chromosomal damage. So -- if you're feeling down, this med can make things hugely worse. Also, exposure to unexpected situations when under the influence of LSD can lead to a panic reaction, which is never a good thing. There's no way to tell how you'll feel if you take it, which explains why it's not that popular a street drug.

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16y ago

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