You can check all known interactions of drugs yourself with the website http://www.drugs.com/drug_interactions.php. Simply type in the drugs you wish to find and select the correct drug from the dropdown menu. All known interactions will then appear.
---- Interactions searched:
* Dilantin (phenytoin) * Zoloft (sertraline) ---- 1 Interaction found:
# Dilantin (phenytoin) and Zoloft (sertraline) (Moderate Drug-Drug) PROBLEM: Two case reports suggest that sertraline may significantly increase phenytoin levels when used concomitantly. The mechanism is thought to be related to inhibition of CYP450 2C9 phenytoin metabolism by sertraline. Other hydantoins may also be affected.
POSSIBLE SOLUTION: Clinical and laboratory monitoring for increased hydantoin levels and toxicity is recommended whenever sertraline is added or dosage is changed. Patients should be advised to notify their physician if they experience symptoms of toxicity (e.g., drowsiness, visual disturbances, change in mental status, seizures, nausea, or ataxia). ----
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Please be more specific with the other medications you had in mind. Dilantin does have many interactions with prescription and OTC medications.
That will be fine. Flexeril is a muscle relaxant. It won't interact with your seizure medication. Remember that it will make you sleepy, though.