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Basically no, due to two reasons:
- First, the drug is incompletely absorbed from the gastrointestinal tract, some of it exits the body unabsorbed along with the feces.
- Second, the absorbed amount of the drug undergoes first-pass metabolism; where the drug enters the hepatic portal system and is partly metabolized by the liver, thus, the amounts of drug reaching the systemic circulation unchanged is even less.
Moreover, its not logical for it to be more than 100%, since bioavailability by definition is the fraction of the amount of the drug administered that reaches the systemic circulation unchanged. It can't be more than 100% unless larger amounts of the drug reaches your circulation than the amount you already took orally, which is impossible.
While it cannot be more than 100% for a single dose, if the drug is administered more often than the period necessary for complete elimination from the body, total serum concentration may be higher than 100% of the single dose. Such is the case with most antibiotics for example, which are administered at intervals of 4-6-12 hours to achieve and maintain plasma concentrations higher than the single dose. (PS I am not a health professional)
What else can I help you with?
Can you have a list of different drugs bioavailability?
cardiovascular drugs
How does first-pass effect affect bioavailability of drugs?
relationship between the first pass effect and bioavailability
How does chemical stability of the drugs in the gastrointestinal tact affect the bio-availability of the drugs?
Bioavailability is used to describe the fraction of an administered dose of unchanged drug that reaches the systemic circulation, so we need chemically stable drug in order to increase the chance of drug absorbance and thus increased bioavailability.
Why is sodium polycrate good?
Sodium polycrate is a good additive in medicine because it acts as a surfactant, helping to dissolve and stabilize medications. It can improve the solubility and bioavailability of poorly water-soluble drugs, making them more effective when taken orally. Additionally, it can enhance the absorption of drugs in the gastrointestinal tract.
Are drugs applied on the tongue topically or orally?
Neither sublingual
Which illegal drugs will produce intoxicating effects when ingested orally?
Marijuana
What is bioavailability as it applies to orally administered drugs?
In layman's terms, bio-availability applies to "how much of this drug, when administered orally, is actually absorbed?" I.e how much of the drug is "available" for the body to utilize?What makes it a more confusing concept is that bio-availablity of the same drug, at the same dosage, is not the same for every person. (Although you can at least hope they are similar, which enables drugs to have standardized dosages). One of the primary (controllable) factors affecting bio-availabilty is diet; some drugs are absorbed best when taken with food, others are absorbed best when taken on an empty stomach. And some drugs' bio-availabilities are very affected by the fat content in recent meals (normally the more fat which is consumed, the less of a drug can be absorbed).
What percent of crashes are caused by drugs?
about 27 percent of teen crashes are related to drugs
What percent of kids do drugs?
About 87% of kids do drugs
What is the difference between a systemic effect and a local effect?
Systemic means that the drug acts in the whole body(usually drugs that are administered orally or i.v),having effect i various parts of the body(e.g:aspirin lowers fever AND thins blood AND eleviates pain AND can induce bleeding in the gastric tract).LOCAL means that the drug only acts in the area where it is administred(e.g:strepsils for a throatache,aciclovir oilment for herpes,etc) and is not absorbed into the bloodflow,therefor does not act in multiple levels of the body.
What is the percent of teens doing drugs?
In 30 days 20 percent of teens have been reported doing drugs.
What drugs have been taken orally and recently an effort should to blank to prevent absorption?
What_drugs_have_been_taken_orally_and_recently_an_effort_should_to-blank-_to_prevent_absorption
