Yes.
And taking high dosages causes seizures, brain damage, and death.
Short answer; Yes. Benedryl or namely Diphenhydramine(the chemical name) can give you a feeling of euphoria. It is not safe to take in large amounts and should not be used in this manner. but if you are going to BE VERY CAREFUL! 25-50 mgs is the normal dose. if you take more than that you could go into respiratory or cardiac arrest. (your heart stops beating, or you stop breathing). Diphenhydramine is commonly used as a sleep aid and it will make you VERY drowsy. so even if you do feel a little 'high' you will likely fall asleep and not even remember it. DO NOT EVER, EVER EXCEED 100 MG'S!!! you could die.
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Its a weird high... not very enjoyable or recreational unless youre trying to escape life for a good 6 hours. At doses of 300mg + you will begin to hallucinate, but not like shrooms or acid. The things you see are real, such as people or objects, and it is near to impossible to distinguish hallucinations from real life. Youll spend a lot of the times talking to people who aren't there or scared of something or someone that looks like its going to hurt you. Using with marijuana increases effects. In my experience, i was really frusturated about people not talking back to me and not being able to pick anything up(because the things weren't actually there.) It is a crazy experience.
Yes - take between 300 and 400 mg and there's no reason you wouldn't get high - I'm a pretty big guy - 6'2" / 200 and 400 mgs get's me messed up for about 4-7 hours. So if you're smaller than me, it will probably last longer for you.
You will have very mild visual hallucinations, like things slightly squashing and stretching. You'll see faint shadows that aren't really there. You'll feel perfectly sober though, it'll feel a bit strange. I did this last night and saw the room swaying as though it were a pirate ship. I woke up and my eyes were numb, on my way to work it appeared I wasnt getting any closer to the mountains I was approaching. The road was like a treadmill. But when I got close to the mountains they popped out at me. I'm still experiencing these effects. You won't get 'high' but you will feel out of it.
diphenhydramine, also known as benedryl or unisom, can get one "high" at higher doses. it can make ppl hallucinate. however, i hear that tolerance can build rather quickly. a typical therapeutic dose is 25-50 mgs. however some ppl can get high at doses as low as 75 to 100mgs. some ppl require higher than that to get "high" but I dont think it is good for the kidneys or liver.