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Yes, they can. But there is a wide variety of effectiveness. The first thing to consider is what type of air purifier you are using. If the air purifier is using a HEPA filter, then it will clean the air. How much air is cleaned depends on a couple of things. The purifier can only clean the air that actually passes through it. In order to do this it has to have a powerful fan. The fan should be able to circulate all the air in the room at least 6 times. If it can do this then it will clean the air.
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