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Amprolium HCl is used to treat coccidiosis of laying hens, growing chickens, turkey, cattle's and different other farm animals, also used as assistance treatment drugs to prevent and control the coccidiosis' spread. Amprolium Hydrochloride is traditional coccidiostatic, and it's used in poultry feed to control coccidiosis. Amprolium Hydrochloride is very good against the hemorrhage-producing coccidia E. tenella and E. necatrix and it has some activity against E. maxima, amprolium hydrochloride is one of the most safety anti-coccidial drugs and be approved by FDA.

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12y ago

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What is the drug resistance of amprolium?

Amprolium is not an organism, so is not an antibiotic in the sense I think you mean. It is an analog of Vitamin B1, and works by preventing the uptake of thiamine (B1) by the organism which causes coccidiosis. Amprolium makes the creature's body an environment hostile to the development of coccidiosis, without actually attacking the coccidiosis organism. It's like a placebo food for the coccidiosis microbe, which gets no nourishment from it. To some degree amprolium also reduces the uptake of thiamine in the creature who is eating amprolium in its feed, so it is only administered until the young chickens are old enough to have built up an immunity to coccidiosis, from low-level environmental exposure to it. Then they are switched to unmedicated feed. (This is fairly common for management of small poultry flocks; I can't speak about the management of large-scale operations.) Using amprolium does not contribute to drug-resistant microbes.


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