Yes, often times when a baby is constipated, the health provider will advise you to insert an anal suppository to help relieve the constipation. In the case of newborns, the suppository is usually broken in half before insertion. Most suppositories safe for babies include glycerin.
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As long as it's the right kind of suppository, and the right dosage, it won't hurt the baby. She might make a fuss when you insert it, but that's just babies.