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Generally, donating plasma is safe, and an excellent activity for helping out others who can use the medications made from it.

However, when donating plasma, you must take certain risk factors into consideration. One major issue for some people with donating plasma is dehydration. Most donation centers give you some saline back through an IV when donating, but that is not always enough to replenish the body's water levels.

Another issue is that your plasma contains many substances that help fight infection. If you donate often, you run the risk of becoming sick more often.

Also, if you are bothered by needles, there is a risk of fainting or passing out from fear, and also from volume displacement in your body.
Yes, donating plasma is very safe. The plasma office will do a health check on you and if it isn't safe for you, then they will not allow you to donate.

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Q: Are there disadvantages to donating plasma?
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