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Flex-a-mine is essentially a Glucosamine, Chondroitin and MSM complex.
From http://www.Arthritis-treatment-and-relief.com/glucosamine-side-effects-msm.html

"Glucosamine is considered relatively safe when taken in recommended dosages. However, some glucosamine side effects can occur.

These supplements are generally well tolerated. The most commonly reported side effects of glucosamine and chondroitin include:

• Nausea
• Diarrhea or constipation
• Heartburn
• Increased intestinal gas

MSM is considered very safe, and side effects are very rare. Side effects that have been reported include:

• Diarrhea
• Skin rash
• Headache
• Fatigue"
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15y ago

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