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ADH works to reabsorb water from the lumen of the collecting ducts in the kidneys back into the interstitial space. As a result, high levels of ADH will result in higher concentrations of aquaporin-2 on the luminal membrane, allowing for H2O reabsorption in the otherwise-H2O-impermeable collecting ducts. As a result, the urine will be more highly concentrated due to the loss of water (back into the blood), reaching an osmolarity of around 1400 mOsm maximum.
In dehydration, ADH levels are high (enables the body to retain more water) and in over-hydration, ADH levels are low (no need for the body to retain water, hence increased micturition)
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What are effects of over hydration and dehydration?
Over hydration will dilute the body's chemical balance. Dehydration will cause organ damage. Both states are to be avoided if you wish to live!
Why are intake and output charts important?
To prevent dehydration or over-hydration
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dehydration!!
Is not a symptom of over-training?
dehydration!!
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Yes, absolutely. That's why they check creatinine levels. The drug tests rely on certain cutoff concentration levels to provide a positive result and therefore overhydrating is an easy way to test negative. Though you may test negative AND dilute, in which case they may make you test again (or not, or fire you, or not).
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pulmonary edema
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because cabbages will take over the world :)
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