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Modic changes, a common observation in MR imaging, are signal intensity changes in vertebral body marrow, adjacent to the endplates of degenerative discs.
Michael T. Modic, MD, professor of radiology and neurology at Case Western in Cleveland, wrote about these changes in the journal Radiology in 1988, and his name has been associated with these changes ever since.
Modic changes take 3 main forms:
Type I
· Decreased signal on T1, and increased signal on T2.
· Represents marrow edema.
· Associated with an acute process.
· Histological examination shows disruption and fissuring of the endplate and vascularized fibrous tissues within the adjacent marrow
Type II - the most common type
· Increased signal on T1, and isointense or slightly hyperintense signal on T2.
· Represents fatty degeneration of subchondral marrow.
· Associated with a chronic process.
· Histological examination shows endplate disruption with yellow marrow replacement in the adjacent vertebral body.
Type I changes convert to Type II changes with time, while Type II changes seem to remain stable.
Type III
· Decreased signal on both T1 and T2.
· Correlate with extensive bony sclerosis on plain radiographs.
· Histological examination shows dense woven bone; hence, no marrow to produce MRI signal.
MODIC CHANGES on MRI
T1
T2
Significance
TYPE 1
¯
Edema
TYPE II
® (or slight)
Fatty Degeneration
TYPE III
¯
¯
Bony Sclerosis
Marrow Edema; at the right C1-C2 articulation
Marrow edema at the right C1-2 articulation most likely
degenerative/mechanical in nature
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What is degenerative endplate changes?
It's an MRI sign that the intervertebral discs are aging.
What does slight progression of degenerative marrow endplate changes at the L5-S1 level mean?
what does slight progression of degenerative marrow in the l5 - s1
What are Osseous structures in scattered endplate degenerative thoracic spine?
Osseous structures refer to the bony components of the spine that may show signs of degeneration or wear over time. In scattered endplate degenerative changes in the thoracic spine, there may be areas of bony spur formation, disc space narrowing, and sclerosis at the endplates, indicating degenerative changes affecting the bones and discs in that region of the spine. These changes can contribute to symptoms such as pain, stiffness, and limited mobility in the thoracic spine.
What is endplate lipping?
Endplate lipping refers to the formation of bony spurs or projections at the edges of the vertebral endplates in the spine. This can be seen on imaging studies like X-rays and may indicate degenerative changes in the intervertebral discs and joints of the spine. It is commonly associated with conditions like osteoarthritis and degenerative disc disease.
What is endplate changes?
Endplate changes is a medical term used to describe the thinning or erosion of the cushioning discs that separate the vertebrae in your spine. This can happen simply from aging.
What is discogenic marrow endplate at C5-6?
Discogenic marrow endplate changes at C5-6 refer to degenerative alterations in the vertebral endplate at that specific level of the cervical spine, likely due to wear and tear over time. This can lead to decreased disc height, altered biomechanics, and potentially contribute to symptoms such as neck pain or radiculopathy. Treatment may involve conservative measures like physical therapy, pain management, or in some cases, surgery.
What is degenerative osseous?
Osseous degenerative changes are changes in the bone density and structure of the spine. These changes often cause pain and curvature of the spine.
What is endplate edema?
Edema is swelling of an extremity or area of the body. A degenerative end plate may be an area that shows up on an x-ray showing breakdown of bone. A physician will need to evaluate and treat.
Is mild sclerosis of Right humeral head caused by degenerative changes?
Mild sclerosis of the right humeral head is often caused by degenerative changes.
What does degenerative change mean?
Degenerative changes usually have to do with changes in the body as it ages. These changes are usually things like arthritis and osteoporosis.
What are degenerative changes?
Degenerative changes occur when the spine makes manifestations on its own. This often results in serious and painful problems related to the back such as osteoporosis or scoliosis.
What does it mean when my mri report says signal loss and volume loss in c4-c5 and c6-c7 with reparative endplate enhancement at c7 superior endplate and in the foramen on the left at c6-c7?
Signal loss and volume loss in the c4-c5 and c6-c7 discs on an MRI report typically indicate degenerative changes or disc degeneration. Reparative endplate enhancement at c7 suggests a healing response to injury or inflammation. The presence of these findings may contribute to symptoms such as neck pain, stiffness, or decreased range of motion.
