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The intrapleual pressure is always below atmospheric pressure. Because of the connection between the two plurae which is similar to two wet pieces of paper adhered to each other, the negative intrapleural pressure helps to expand the lungs during ventilation. If intrapleural pressure was equal to atmospheric pressure, the lungs would collapse. Such a case is seen in a penetration of the thoracic cavity (pneumothorax), where a puncture in the thoracic cavity, and subsequently the plurae, will result in a collapsed lung.

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Q: What happens if intrapleural pressure equal atmospheric pressure?
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Why is intrapleural pressure negative rather than positive?

Because the negative pressure is the major factor preventing the lungs from collapsing. If the intrapleural pressure became equal to atmospheric pressure the lungs would recoil and collapse.


What is the concept of equal pressure point?

Equal pressure point (EPP) is the point where Intrapleural pressure and Alveolar pressure are equal. This is similar to the Starling resistor concept in the lung. Instead of flow being determined by the difference between alveolar and mouth pressure- flow is determined by the difference between alveolar and Intrapleural pressure difference. In forced expiration, both intrapleural pressure and alveolar pressure will increase. However alveolar pressure will decrease along the length of the airway until a pressure of zero at the mouth, whereas intrapleural pressure will remain the same. Therefore there will be a point where intrapleural pressure will be equal and subsequently greater than alveolar pressure. If the EPP occurs in the larger cartilaginous airways, the airway remains open. However, if the EPP is in the smaller airways, it will collapse. Increasing the force of expiration does not overcome EPP since it will increase both alveolar and intrapleural pressure. Another interesting concept is that EPP moves distally as expiration progresses because as air leaves the alveolar unit, the pressure in the alveolar decreases hence the pressure in the airway decreases as well. EPP is the cause of dynamic airway compression.


If the pressure becomes equal to the atmospheric pressure the lung collapses?

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