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According to the Progeria Research Foundation progeria is caused by a 'sporadic autosomal dominant' mutation.

A mutation is a change in a gene.

Sporadic means that the mutation occurs at random, and is not usually inherited from a parent.

Autosomal means that the gene is located on one of the 22 pairs of non-sex chromosomes in the cell nucleus. In fact research has shown that the gene is on chromosome number one.

Dominant means that you only need one copy of the gene to develop the disease. So one chromosome in the pair can have a normal gene and the other chromosome can have the mutant gene.

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14y ago

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