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The ratio of albumin to globulin in blood serum, plasma, cerebrospinal fluid, or urine. Albumin-globulin=AG ratio. Normal adult ranges are as follows: Albumin is 3.5-5; Globulin is 2.6-4.6 which makes the normal range for the ratio 0.8-2.0.

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The increase of the albumin-to-globulin (AG) ratio can be attributed to several factors. A higher albumin level, often due to dehydration, liver disease, or malnutrition, can elevate the ratio. Conversely, a decrease in globulin levels, which may result from certain medical conditions such as immunodeficiencies or liver dysfunction, can also contribute to an increased AG ratio. Additionally, conditions that affect protein synthesis or breakdown can influence the balance between albumin and globulin levels, leading to variations in the AG ratio.


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