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Yes, you can install one copy of Sims 2 on as many computers as you want. However, you need the Sims 2 disc to start up the game. You can take this Disc out after you have gotten into a Neighbourhood and start up the other Sims 2, however, the Disc will be required for loading screens sometimes (Neighbourhood -> House etc.)
Yes. But every time you want to play it you need the disc. Also, if you have any expansion packs or stuff packs you can use that disc for one computer and the one without the expansion/stuff pack with the original Sims 3 disc (I've done it before)
When you purchase The Sims 2 University its comes with 2 discs. Called the Expansion Pack. There is Disc One with a man on it and Disc two with a woman on it. If you try to put in disc one first it won't work because a message will pop up saying. (This product requires an installed copy of The Sims 2. Please install the Sims 2 before installing this product) Now that may seem confusing but not really. Insert Disc two. Press Open. After that you press Run As. It will run for a little while to write down all the saved files on your disc. If something goes wrong with the download press Retry. If that doesn't work then you might have to go through all of your files to check if any The Sims 2 games are saved. What might be causing to decline to download is probably because you have other saved files of The Sims 2. Please uninstall all of your The Sims 2 game files. Then try to download disc two again. It should work. If it works take out disc two and put in disc one with the man on it. Then press Next to that your English or Espanol. Then it should install. If that does not work then I'm not sure what will.
You install Sims 2 on Vista just as you would on former Windows OSs. You need to have the original Sims2 base game or you can use one of the combo packs as long as the riginal, Sims 2 bade game is included. Just insert the 1st disk into your disc drive and it sould auto-install. From there, the installer will (should) prompt you to insert the proceeding disks. If it doesn't autoinstall, go to Start>(My) Computer and then double click on the drive that contains the disc. This should start the process.
Mount the disc image file (.iso) of the game using magic iso, start with the first disc if there is more than one, then autorun should start. Magic iso is a virtual disc drive, so when using it treat the iso file like a real disc.