After you obtain the National Pokédex and visited the Pal Park, Professor Oak appears in the southernmost house in Eterna City.
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his house is in eterna city right next to the gym. hoped this helped
If you have the National Pokedex, Prof. Oak will be in a house in southern Eterna City.
He is east of Fuchsia City, in the gaurd house separating route 15 from the city. Go up the stairs, and you will find his aide.
First off, talk to Prof. Oak in Eterna City (he lives in the house in the southwest end next to the gym) and he will the three have been seen around Sinnoh. Track them with your Marking Map Poketch app. If Oak is not in his home, you may have to talk to him first in Pal Park, afterwards he will be in Eterna City.