When the 3ds came out. The cartridges are now different.
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game boy advance can be play on a ds to
yes
Sure you can, if you have the original Nintendo DS or the Nintendo DS Lite you can play the GBA version of Pokémon Sapphire. Otherwise there are third party DS cartridges you buy to play Sapphire.
Slot 1 is the slot at the top of the DS, for DS games. Slot 2 is the slot at the bottom of the DS, for GBA cartridges.
Regular DS games are not region locked. A DS game cartridge from the US will work fine on a UK DS system.