nothing does. although it is possible in a member pvp world to drop them. i would just buy them. pvp can get boring and if you lag in a fight and can't eat you may lose your stuff like i did. lost full dragon plate and full helm.
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Rune Claws. It's stats are off the hook.
Dragons. Their hides go for loads of coins, expecially the Black Dragon Hides.
Fire Giant's tend to occasionally drop Rune Battle axes.
go to fusionfaller1.tk gives you the information on what monster drops what like he hex staff
The quest "Rune Mysteries" is a prerequisite to mine rune essence, and to make the actual runes.There is a rune essence mine. Go to Aubury (south of the eastern Varrock bank); he will teleport you if you did the quest.You can of course buy rune essence from the Grand Exchange - rune essence that was obtained and sold by other players.You also get small amounts of rune essence as drops from certain monsters.