They are both very great games i enjoyed them. Prototype is on the Xbox 360 and the PS3, but infamous is only on the PS3 but may soon be coming out on the 360 POSSIBLY! As for the gameplay infamous you are cole delivering a package when all the sudden the package explodes and you have these electric powers. In infamous you can shape your destiny choose the good karma or bad karma. This game you can jump up building by grabbing on to ledges. This game is a comic book nerds type of game. But this game is fun to free play in even though you can get more powers in Prototype, the fun lasts longer in free play in infamous. Now.....
Prototype is a game where you are a person named Alex Mercer and wake up in a experiment facility about to be cut open then you wake up. In prototype is more of an action type game and in it you can consume others and become them, and you can have claws, blades, armor, shields, whips, etc. It is more fun while you are doing missions than to free play. You donnot have to do this but i don't beat the last level because when I do the city is 98 percent Millitary zones which is bad cause if you do ONE thing wrong they all attack you and it is also 98 percent infected with Zombies. Prototype is more bloody but also fun at the same time you can highjack tanks and heli's. When you wake up you don't remember anything but when you consume more people you gain memory of your past life. I have had more play time in infamous so I don't have much more to say about Prototype. But I don't know what kind of person you are so I cant really tell which is better but hopefully after reading this you can figure it out. If this didnt help watch these two videos. This is the Gameplay of the the two games: http://www.YouTube.com/watch?v=tNBf19aJ_uI
This is talking about what you can do in the two games/Grudge Match: http://www.youtube.com/watch?v=-ObHLztmGwM
So in short - they are both crap ;)
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You just have free roam, where you can do what you want and replay missions to get a better score.
I'm going to assume you mean Bad Company 2. Then I'll say that they are very different. BC2 (Bad Company 2) is a first-person shooter while inFamous is...a third person shooter I would say, but you are firing lightning rather than bullets. BC2 is rated "M" by the ESRB; iF is rated "T". inFamous has about 20 hour game, but no multiplayer. (In my opinion, adding that that would ruin the game). BC2 is only 8 hours or so, but it has multiplayer. The multiplayer is just as good/better than Modern Warfare 2, but has less modes. Personally, I like inFamous better.
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1 purpose of a prototype is to find design flaws. If any were made, another prototype might be made. If not, the next step would be manufacturing.
there are 39 story missions in inFAMOUS