As far as I know the answer is Uncharted 2: Among Thieves.
It won a whopping 111 GOTY awards.
According NaughtyDog both Uncharted 2: Among Thieves and The Last of Us have won over 200 Game of the Year awards, but i don't know which has more
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Uncharted 2: Among Thieves and Last of Us have both won over 200 Gam of the year awards, according to Naughty Dog
I searched that and I found many sites and the VGA's (Video Game Awards) have put Resident Evil 4 as game of the year 2005.
There are a few, BUT! The one that's won most awards for bein scary are the CONDEMNED Games for 360, especially Condemned 2
I honestly don't know, as I haven't ever tried to earn all the awards. If you go to http://www.uhs-hints.com/uhsweb/hints/nancydrew19/88.php you can find out how to get the awards. My recommendation is that you play the game and try to get all the awards.
It won Best Indie Game of the Year Award, 2011. It was also the GameInformer's PC Game of the Year.